Cut back with confidence. Our comprehensive, medication-based programme is perfect for anyoneseeking discreet, effective treatment rooted in science.
On-Demand Prescription whenever you need it (subject to clinician approval)
Guided onboarding programme - expert content delivered as you go
Continued support through all stages of your journey
Programme based on targeted Naltrexone or Nalmefene, according to The Sinclair Method (TSM), backed by over 90 clinical trials and a 78% success rate
Weekly online group support sessions, led by our world-class TSM coaches
Clinician-led reviews included with every medication refill request
Access to clinical support at no extra cost
Choose your plan
3 months - £480
6 months - £600
12 months - £840
Pay by card or choose Klarna at checkout and split your programme fee into 3 interest-free payments.
Please note: Medication costs are not included in the programme fee.
Initial Consultation Required:
Before joining the programme, you'll complete a one-off £50 suitability assessment to determine whether you're clinically eligible. Programme fees apply only if you're approved and decide to join.
Medication cost:
Medication is paid for separately at £99 per 28 tablets, dispensed and shipped via our pharmacy partner, Blueco.
Liver Function Test:
For ongoing treatment, a recent LFT result will be required. Existing results can be submitted, or testing can be arranged through us from £41.
3 months
Cut back with confidence. A three-month programme of discreet, effective treatment rooted in science - designed to get you started without delay.
£480 total
6 months
The same discreet, science-backed treatment as Kickstart, at 31% lower monthly cost across six months.Ideal for those ready to go further.
£600 total
12 months
Twelve months of discreet, science-backed treatment - the lowest-priced annual alcohol reductionprogramme in the UK. Built for lasting, meaningful change.
£840 total
This is a discreet and structured programme for reducing your alcohol consumption, built around The Sinclair Method and supported by expert clinical guidance at every step. Everything you need to makemeaningful, lasting change is included: onboarding, clinician access, regular check-ins, and weekly groupsupport.
Choose the plan that works for you - 3, 6, or 12 months, and steadily build new habits at your own pace,all while supported by our expert guidance. This is the quiet reset. No pressure, no noise, just theopportunity to drink less and grow more.
You can reach out to Nul anytime at hello@choosenul.com for clarifications or if you would like further advice. Don’t forget that during your programme, you will have access to check-ins with a registered clinician once a month to discuss how your treatment is going. And if needed, you will be able to reach a clinician for support at any time outside of these check-ins by getting in touch.
Not necessarily. You'll complete an online assessment and meet with a registered clinician trained in alcohol reduction by our partners at Blueco Healthcare, who will review your medical history and liver function tests. The clinician will be able to review your medical record and contact your GP if they need more information.
Yes. Not everyone wants to quit entirely, and abstinence is not a requirement for participation in the programme. You’ll take your medication 1–2 hours before drinking, which, over time, helps reduce cravings and the compulsion to drink.
The medication prescribed is either Naltrexone or Nalmefene. They are both opioid antagonists that block the endorphin response alcohol typically produces in the brain. This reduces the rewarding effects of drinking, helping you break free from habitual patterns over time. As the brain stops associating alcohol with pleasure or relief, the urge to drink weakens. This is the foundation of the Sinclair Method®, which underpins Nul’s treatment programmes.
¹Sinclair, John – Clinical Studies, 2001
Before drinking? Take it as soon as you remember and wait at least 1-2 hours as directed before drinking.
After drinking has started? Take it as soon as possible, but note that the extinction effect may be weaker.
Try to never skip your dose entirely.
Many people report that alcohol feels less satisfying while on Naltrexone. This is a sign that the extinction effect is working – the reward loop that was so entrenched in your neural pathways is slowly breaking down.
The effect on physical cravings is noticeable almost immediately after taking Nul, but the emotional and psychological shifts take longer. Some people begin noticing changes within weeks, while others may take several months. Like when trying to make any big life changes, consistency and patience are key.
Yes. The Nul Medication Programme is based on The Sinclair Method®, which is backed by over 90 clinical trials and has a 78% success rate in reducing alcohol use. It has been studied for decades and is widely recognised as an evidence-based approach to alcohol reduction.
¹Sinclair, John – Clinical Studies, 2001
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© 2025 NUL Health Limited.
Registration No: 16119526. All rights reserved.
Healthcare Provider:
Blueco Healthcare. Registration: Care Quality Commission (CQC), ID: 1-19176166626.
Registered Pharmacy:
Blueco Healthcare, 468 Ranglet Road, Walton Summit, Bamber Bridge, Preston, PR5 8AR GPhC Reg No: 9013068.
Superintendant Pharmacist:
Haroon Amanji. GPhC Reg No: 2070534.
